Symbol
Name
ID

Traf3
TNF receptor-associated factor 3
MGI:108041

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

decreased B cell apoptosis

decreased thymocyte number

enlarged spleen

abnormal B cell differentiation

increased transitional stage B cell number

decreased double-positive T cell number

decreased mature B cell number

increased follicular B cell number

increased marginal zone B cell number

increased B cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased T cell number

decreased leukocyte cell number

abnormal leukocyte morphology

spleen hypoplasia

abnormal spleen germinal center morphology

increased spleen white pulp amount

abnormal B cell physiology

increased IgA level

increased IgG2a level

increased IgG2b level

increased IgG3 level

decreased IgG level

increased IgG level

increased IgM level

abnormal T cell physiology

Availability

Mouse Genotype

Traf3^m1Btlr/Traf3^m1Btlr

Traf3^m2Btlr/Traf3^m2Btlr

Traf3^tm1Bal/Traf3^tm1Bal

Traf3^tm1Bshp/Traf3^tm1Bshp
Cd19^tm1(cre)Cgn/Cd19⁺ (conditional)

Cd19^tm1(cre)Cgn/Cd19⁺
Traf3^tm1Rbr/Traf3^tm1Rbr (conditional)

Tg(Lck-cre)I57Jxm/?
Traf3^tm1Rbr/Traf3^tm1Rbr (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23